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IBM, Moderna Partner on Quantum for BiotechIBM, Moderna Partner on Quantum for Biotech

Pharmaceutical company Moderna is working with IBM to evaluate whether a quantum algorithm could accurately predict stable mRNA structures more accurately than current technology.

Berenice Baker, Editor, Enter Quantum, co-editor AI Business

May 24, 2024

1 Min Read
A person's hands, one holding a pen, over a backlit DNA sequence
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Pharmaceutical company Moderna is working with IBM to evaluate whether a quantum algorithm could accurately predict stable mRNA structures more accurately than current technology.

This could lead to a better understanding of gene expression, regulation and development of gene-based treatments.

Moderna shot to public awareness after it used its established R&D resources to develop a COVID-19 vaccine at record speed at the height of the pandemic.

A recent IBM blog on the future of quantum computing in biotech explored how the companies are collaborating to better predict secondary structure in mRNA.

This process is a critical task in molecular biology that challenges classical computers as the sequence gets longer and accelerating the process could help develop novel mRNA vaccines more efficiently.

Moderna and IBM are first benchmarking using a quantum computer against a classical Cplex protein analysis solver. Cplex is a software tool that solves complex optimization problems.

They will run a quantum algorithm called CVaR VQE on randomly generated mRNA nucleotide sequences and compare how it performs against existing processes in accurately predicting stable mRNA structures.  

This benchmark proves quantum computing has a role in delivering insights into mRNA dynamics. As a next step, IBM and Moderna plan to use the new algorithm with longer mRNA sequences that Cplex and classical computing can.

Related:IBM Targets Quantum Advantage with Expanded Software

About the Author

Berenice Baker

Editor, Enter Quantum, co-editor AI Business, Informa TechTarget

Berenice is the editor of Enter Quantum and co-editor of AI Business. She has over 20 years of experience as a technology journalist, having previously worked at The Engineer and Global Defence Technology.

Before that, she worked as an IT consultant, fuelling her passion for technology and innovation. She graduated with one of the country's first-ever IT degrees so long ago it coincided with Tim Berners-Lee inventing the World Wide Web.

Berenice lives in north London with her cat Huxley. In her spare time, she enjoys going to music gigs, museums and galleries, dabbling in art and playing guitar (badly).

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